Acanthosis nigricans: A marker for hyperinsulinemia

被引：20

作者：

Brockow, K

Steinkraus, V

Rinninger, F

Abeck, D

Ring, J

机构：

[1] Universitäts-Krankenhaus Eppendorf, Hamburg

来源：

PEDIATRIC DERMATOLOGY | 1995年 / 12卷 / 04期

关键词：

D O I：

10.1111/j.1525-1470.1995.tb00193.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

A 12-year-old girl developed acanthosis nigricans due to increased levels of serum insulin. Hyperinsulinemia has been recognized as the underlying cause in most cases of acanthosis nigricans. In this paper we outline a typical clinical case with special regard to the proposed pathogenesis.

引用

收藏

页码：323 / 326

页数：4

相关论文

共 14 条

[1] EXCESS INSULIN BINDING TO INSULIN-LIKE GROWTH-FACTOR RECEPTORS - PROPOSED MECHANISM FOR ACANTHOSIS NIGRICANS [J].

CRUZ, PD ;

HUD, JA .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1992, 98 (06) :S82-S85

[2] SIGNIFICANCE OF ACANTHOSIS NIGRICANS [J].

CURTH, HO .

AMA ARCHIVES OF DERMATOLOGY AND SYPHILOLOGY, 1952, 66 (01) :80-100

[3] ACANTHOSIS NIGRICANS, INSULIN ACTION, AND HYPERANDROGENISM - CLINICAL, HISTOLOGICAL, AND BIOCHEMICAL FINDINGS [J].

DUNAIF, A ;

GREEN, G ;

PHELPS, RG ;

LEBWOHL, M ;

FUTTERWEIT, W ;

LEWY, L .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1991, 73 (03) :590-595

[4] CUTANEOUS INSULIN REACTION RESEMBLING ACANTHOSIS NIGRICANS [J].

FLEMING, MG ;

SIMON, SI .

ARCHIVES OF DERMATOLOGY, 1986, 122 (09) :1054-1056

[5]

Grunfeld C, 1984, Spec Top Endocrinol Metab, V6, P193

[6] SYNDROMES OF INSULIN RESISTANCE AND ACANTHOSIS NIGRICANS - INSULIN-RECEPTOR DISORDERS IN MAN [J].

KAHN, CR ;

FLIER, JS ;

BAR, RS ;

ARCHER, JA ;

GORDEN, P ;

MARTIN, MM ;

ROTH, J .

NEW ENGLAND JOURNAL OF MEDICINE, 1976, 294 (14) :739-745

[7]

MATUSOKA LY, 1987, AM J MED, V83, P719

[8]

MIRSA P, 1986, J INVEST DERMATOL, V87, P264

[9] ACANTHOSIS NIGRICANS [J].

SCHWARTZ, RA .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1994, 31 (01) :1-19

[10]

STUART CA, 1989, AM J MED, V87, P269