RESISTANCE OF CANDIDA-ALBICANS BIOFILMS TO ANTIFUNGAL AGENTS IN-VITRO

被引：313

作者：

HAWSER, SP ^{[1
]}

DOUGLAS, LJ ^{[1
]}

机构：

[1] UNIV GLASGOW,INST BIOMED & LIFE SCI,DIV MOLEC & CELLULAR BIOL,MICROBIOL LAB,GLASGOW G12 8QQ,LANARK,SCOTLAND

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1995年 / 39卷 / 09期

关键词：

D O I：

10.1128/AAC.39.9.2128

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Biofilms formed by Candida albicans on small discs of catheter material were resistant to the action of five clinically important antifungal agents as determined by [H-3]leucine incorporation and tetrazolium reduction assays. Fluconazole showed the greatest activity, and amphotericin B showed the least activity against biofilm cells. These findings were confirmed by scanning electron microscopy of the biofilms.

引用

页码：2128 / 2131

页数：4

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