FERTILIZATION AND PREGNANCY ACHIEVED BY INTRACYTOPLASMIC INJECTION OF SPERM RETRIEVED FROM TESTICULAR BIOPSIES

Objective: To determine if intracytoplasmic sperm injection using testicular sperm is effective in the treatment of infertile couples with obstructive azoospermia. Design: Case report. Setting: Tertiary care teaching medical center. Methods: Intracytoplasmic sperm injection was performed in two patients using testicular sperm after microsurgical epididymal sperm aspiration failed. Results:In both cases fertilization and embryos resulted. One patient conceived and delivered triplets. There was no evidence of chromosomal abnormality or congenital malformation. Conclusions: Intracytoplasmic sperm injection using sperm extracted from testicular biopsy appears to be effective in the treatment of infertile couples with obstructive azoospermia when microsurgical sperm aspiration fails.