STRUCTURES OF BACTERIAL IMMUNOGLOBULIN-BINDING DOMAINS AND THEIR COMPLEXES WITH IMMUNOGLOBULINS

被引：95

作者：

TASHIRO, M

MONTELIONE, GT

机构：

[1] Center for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, NJ 08854-5638

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1995年 / 5卷 / 04期

关键词：

D O I：

10.1016/0959-440X(95)80031-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three-dimensional structures are now available for several immunoglobulin binding domains from bacterial proteins A, G, and L. X-ray diffraction and NMR experiments on complexes of these domains with portions of immunoglobulins have revealed common structural themes used in these interactions. These data expand our understanding of structure/function relationships in these molecular recognition processes and provide the basis for rational design of artificial immunoglobulin-binding molecules.

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页码：471 / 481

页数：11

相关论文

共 61 条

[1] 1.67-ANGSTROM X-RAY STRUCTURE OF THE B2 IMMUNOGLOBULIN-BINDING DOMAIN OF STREPTOCOCCAL PROTEIN-G AND COMPARISON TO THE NMR STRUCTURE OF THE B1 DOMAIN [J].

ACHARI, A ;

HALE, SP ;

HOWARD, AJ ;

CLORE, GM ;

GRONENBORN, AM ;

HARDMAN, KD ;

WHITLOW, M .

BIOCHEMISTRY, 1992, 31 (43) :10449-10457

[2]

AKERSTROM B, 1989, J BIOL CHEM, V264, P19740

[3] THERMODYNAMIC ANALYSIS OF THE FOLDING OF THE STREPTOCOCCAL PROTEIN-G IGG-BINDING DOMAINS B1 AND B2 - WHY SMALL PROTEINS TEND TO HAVE HIGH DENATURATION TEMPERATURES [J].

ALEXANDER, P ;

FAHNESTOCK, S ;

LEE, T ;

ORBAN, J ;

BRYAN, P .

BIOCHEMISTRY, 1992, 31 (14) :3597-3603

[4] KINETIC-ANALYSIS OF FOLDING AND UNFOLDING THE 56-AMINO ACID IGG-BINDING DOMAIN OF STREPTOCOCCAL PROTEIN-G [J].

ALEXANDER, P ;

ORBAN, J ;

BRYAN, P .

BIOCHEMISTRY, 1992, 31 (32) :7243-7248

[5] HEMATOPOIETIC RECEPTORS AND HELICAL CYTOKINES [J].

BAZAN, JF .

IMMUNOLOGY TODAY, 1990, 11 (10) :350-354

[6] FIRST-PRINCIPLES CALCULATION OF THE FOLDING FREE-ENERGY OF A 3-HELIX BUNDLE PROTEIN [J].

BOCZKO, EM ;

BROOKS, CL .

SCIENCE, 1995, 269 (5222) :393-396

[7] THE STABILITY AND UNFOLDING OF AN IGG BINDING-PROTEIN BASED UPON THE B-DOMAIN OF PROTEIN-A FROM STAPHYLOCOCCUS-AUREUS PROBED BY TRYPTOPHAN SUBSTITUTION AND FLUORESCENCE SPECTROSCOPY [J].

BOTTOMLEY, SP ;

POPPLEWELL, AG ;

SCAWEN, M ;

WAN, T ;

SUTTON, BJ ;

GORE, MG .

PROTEIN ENGINEERING, 1994, 7 (12) :1463-1470

[8]

BOYLE MDP, 1990, BACTERIAL IMMUNOGLOB, V1

[9] RIBBON MODELS OF MACROMOLECULES [J].

CARSON, M .

JOURNAL OF MOLECULAR GRAPHICS, 1987, 5 (02) :103-&

[10] MUTATIONAL ANALYSIS OF THE INTERACTION BETWEEN STAPHYLOCOCCAL PROTEIN-A AND HUMAN IGG(1) [J].

CEDERGREN, L ;

ANDERSSON, R ;

JANSSON, B ;

UHLEN, M ;

NILSSON, B .

PROTEIN ENGINEERING, 1993, 6 (04) :441-448

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