ANTITUMOUR AGENTS .2. ASYMMETRIC-SYNTHESIS OF (S)-CAMPTOTHECIN

被引：43

作者：

EJIMA, A ^{[1
]}

TERASAWA, H ^{[1
]}

SUGIMORI, M ^{[1
]}

TAGAWA, H ^{[1
]}

机构：

[1] DAIICHI PHARMACEUT CO LTD,RES INST,KITAKASAI 1-16-13,EDOGAWA KU,TOKYO 134,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 01期

关键词：

D O I：

10.1039/p19900000027

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of (S)-camptothecin by a novel diastereoselective ethylation process is described.

引用

收藏

页码：27 / 31

页数：5

相关论文

共 22 条

[1] BORSCHE W, 1943, CHEM BER, V76, P1099
[2] SYNTHESIS AND CIRCULAR-DICHROISM OF (5S)-1-AZABICYCLO[3.2.0]HEPTAN-7-ONE
BUSSON, R
VANDERHAEGHE, H
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (23) : 4438 - 4441
[3] Cai J-C., 1983, ALKALOIDS CHEM PHARM, VVol. 21, P101
[4] TOTAL SYNTHESIS OF NATURAL 20(S)-CAMPTOTHECIN
COREY, EJ
CROUSE, DN
ANDERSON, JE
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1975, 40 (14) : 2140 - 2141
[5] THE PREPARATION OF 2(1H)-PYRIDINONES AND 2,3-DIHYDRO-5(1H)-INDOLIZINONES VIA TRANSITION-METAL MEDIATED COCYCLIZATION OF ALKYNES AND ISOCYANATES - A NOVEL CONSTRUCTION OF THE ANTITUMOR AGENT CAMPTOTHECIN
EARL, RA
VOLLHARDT, KPC
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1984, 49 (25) : 4786 - 4800
[6] ANTITUMOR AGENTS .1. ASYMMETRIC-SYNTHESIS OF (S)-CAMPTOTHECIN
EJIMA, A
TERASAWA, H
SUGIMORI, M
TAGAWA, H
[J]. TETRAHEDRON LETTERS, 1989, 30 (20) : 2639 - 2640
[7] GOVINDAC.TR, 1972, INDIAN J CHEM, V10, P453
[8] PLANT ANTI-CANCER AGENTS .10. ISOLATION OF CAMPTOTHECIN AND 9-METHOXYCAMPTOTHECIN FROM ERVATAMIA-HEYNEANA
GUNASEKERA, SP
BADAWI, MM
CORDELL, GA
FARNSWORTH, NR
CHITNIS, M
[J]. JOURNAL OF NATURAL PRODUCTS, 1979, 42 (05): : 475 - 477
[9] HSU JS, 1977, HUA HSUEH HSUEH PAO, V35, P193
[10] CAMPTOTHECIN - CHEMISTRY, BIOGENESIS AND MEDICINAL CHEMISTRY
HUTCHINSON, CR
[J]. TETRAHEDRON, 1981, 37 (06) : 1047 - 1065