A SIMPLE AND UNAMBIGUOUS SYNTHESIS OF ALPHA,ALPHA-DIHALOGENO AND ALPHA,ALPHA'-DIHALOGENO KETONES

被引：30

作者：

BARLUENGA, J ^{[1
]}

LLAVONA, L ^{[1
]}

CONCELLON, JM ^{[1
]}

YUS, M ^{[1
]}

机构：

[1] UNIV ALICANTE,FAC CIENCIAS,DEPT QUIM ORGAN,E-03690 ALACANT,SPAIN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 02期

关键词：

D O I：

10.1039/p19910000297

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient method for the unambiguous preparation of alpha,alpha'-dihalogeno ketones 3 from in situgenerated chloromethyllithium and alpha-chloro or alpha-bromo carboxylic acid esters 1 at -78-degrees-C, is described. The unambiguous preparation of alpha,alpha,-dihalogeno ketones 7 by using in situ-generated dihalogenomethyllithium and carboxylic acid esters 5 at -78-degrees-C is also reported.

引用

页码：297 / 300

页数：4

共 39 条

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