A MILD HYDRATION OF NITRILES INTO AMIDES

被引：32

作者：

BREUILLES, P ^{[1
]}

LECLERC, R ^{[1
]}

UGUEN, D ^{[1
]}

机构：

[1] ECOLE EUROPEENNE HAUTES ETUD IND CHIM,CNRS,SYNTH ORGAN LAB,F-67008 STRASBOURG,FRANCE

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 09期

关键词：

D O I：

10.1016/S0040-4039(00)76229-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Stirring mixtures of beta-hydroxynitriles with manganese dioxide, deposited onto silica gel for a few days at room temperature resulted in the formation of the corresponding amides in fair to good yields. The unprecedented conversion of 3-hydroxyglutarodinitrile into the corresponding monoamide has been performed by this methodology.

引用

页码：1401 / 1404

页数：4

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