ASYMMETRIC-SYNTHESIS OF CYCLOPENTYLAMINE DERIVATIVES, INTERMEDIATES FOR CARBOCYCLIC NUCLEOSIDE SYNTHESIS - CARBOCYCLIZATION OF 2-AMINO-5-HEXENYL RADICALS

被引：9

作者：

MARCOCONTELLES, J

BERNABE, M

机构：

[1] Instituto de Química Orgánica (CSIC), 28006 Madrid

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 34期

关键词：

D O I：

10.1016/S0040-4039(00)73433-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The carbocyclization of 2-amino-5-hexenyl radicals leading to aminocyclopentane derivatives is described for the first time. The tributyltin hydride + AIBN mediated free radical cyclization of the chiral recursors 17-19 and 24 gives compounds 25, 27 and 28, respectively, in good yield.

引用

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页码：6361 / 6364

页数：4

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