AXOTOMY-INDUCED CHANGES IN CYTOCHROME-OXIDASE ACTIVITY IN THE CAT TROCHLEAR NUCLEUS

被引：14

作者：

IANNUZZELLI, PG ^{[1
]}

WANG, XH ^{[1
]}

WANG, YC ^{[1
]}

MURPHY, EH ^{[1
]}

机构：

[1] MED COLL PENN,DEPT ANAT & NEUROBIOL,PHILADELPHIA,PA 19129

来源：

BRAIN RESEARCH | 1994年 / 637卷 / 1-2期

关键词：

CYTOCHROME OXIDASE; AXOTOMY; REGENERATION; MOTONEURON;

D O I：

10.1016/0006-8993(94)91243-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Following a unilateral section of the trochlear nerve, the effects of axotomy on cytochrome oxidase levels in the trochlear nucleus were studied. Cytochrome oxidase levels in the axotomized nucleus were significantly lower than in the control nucleus. The maximal decrease was observed at 2 weeks. Following partial restoration during weeks 3 and 4, cytochrome oxidase levels stabilized at levels only slightly below normal. Since a significant number of trochlear motoneurons die following axotomy, the restoration of cytochrome oxidase levels close to normal suggests that the surviving neurons may compensate for an increased load with a permanent increase in oxidative metabolism.

引用

页码：267 / 272

页数：6

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