Impact of thrombus aspiration on angiographic and clinical outcomes in patients with ST-elevation myocardial infarction

被引：18

作者：

Beaudoin, Jonathan ^{[1
]}

Dery, Jean-Pierre ^{[1
]}

Lachance, Philippe ^{[1
]}

Bertrand, Olivier F. ^{[1
]}

Larose, Eric ^{[1
]}

Rodes-Cabau, Josep ^{[1
]}

Noel, Bernard ^{[1
]}

Barbeau, Gerald ^{[1
]}

Proulx, Guy ^{[1
]}

Nguyen, Can ^{[1
]}

Roy, Louis ^{[1
]}

Gleeton, Onil ^{[1
]}

Rinfret, Stephane ^{[1
]}

Delarochelliere, Robert ^{[1
]}

机构：

[1] Quebec Heart & Lung Inst, Quebec City, PQ, Canada

来源：

CARDIOVASCULAR REVASCULARIZATION MEDICINE | 2010年 / 11卷 / 04期

关键词：

Acute myocardial infarction; Primary percutaneous coronary intervention; Thrombectomy; Angioplasty;

D O I：

10.1016/j.carrev.2009.05.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI) may be limited by thrombus embolization. Export aspiration catheter (EAC) is a thrombectomy device which may enhance angiographic results, but its impact on clinical outcomes is unclear. This trial objective was to assess the impact of EAC on angiographic and clinical outcomes in patients with STEMI. Methods: All STEMI patients undergoing primary or rescue PCI in a tertiary care center were included. Patients were divided in two groups according to the use of the EAC. Patients were followed up prospectively for death, reinfarction, revascularization, or stroke. Thrombolysis In Myocardial Infarction (TIMI) flow in the culprit vessel was assessed before and after PCI. Results: Included in the analysis were 535 patients. EAC was used in 165 patients before angioplasty (Group 1) and 370 patients underwent PCI without thrombus aspiration (Group 2). More patients in Group 1 had initial TIMI flow 0-1 compared to Group 2 (88% vs. 62%, Pb < 001). Proportion of patients with a final TIMI flow 3 was the same in both groups (89.1% vs. 87.6% for Groups 1 and 2, respectively; P =. 67). An analysis restricted to patients with initial TIMI flow 0-1 yielded similar results. No difference in clinical outcomes was observed between the two groups (P =. 70). Conclusions: Selective use of the EAC based on the judgment of operators results in excellent angiographic and clinical results. Further clinical investigation is needed to definitely answer whether thromboaspiration needs to be performed in all STEMI patients undergoing primary PCI. Crown Copyright (C) 2010 Published by Elsevier Inc. All rights reserved.

引用

页码：218 / 222

页数：5

共 14 条

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