BIOREDUCTIVE ALKYLATION AS A TRIGGER FOR TOXIC EFFECTS OF DYNEMICIN

被引:81
作者
SEMMELHACK, MF
GALLAGHER, J
COHEN, D
机构
[1] Department of Chemistry, Princeton University, Princeton
关键词
D O I
10.1016/0040-4039(90)80005-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The endiyne derivative, dynemicin, is postulated to undergo bioreductive cis ring opening of a benzylic epoxide and activate the endiyne unit for Bergman rearrangement to an arene-1,4-diyl. © 1990.
引用
收藏
页码:1521 / 1522
页数:2
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