PURIFICATION AND CHARACTERIZATION OF A NEW HEAT-STABLE ENTEROTOXIN PRODUCED BY VIBRIO-CHOLERAE NON-01 SEROGROUP HAKATA

被引：25

作者：

ARITA, M

HONDA, T

MIWATANI, T

OHMORI, K

TAKAO, T

SHIMONISHI, Y

机构：

[1] RES INST MICROBIAL DIS, 3-1 YAMADAOKA, SUITA, OSAKA 565, JAPAN

[2] OSAKA UNIV, INST PROT RES, SUITA, OSAKA 565, JAPAN

来源：

INFECTION AND IMMUNITY | 1991年 / 59卷 / 06期

关键词：

D O I：

10.1128/IAI.59.6.2186-2188.1991

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The possible production of a heat-stable enterotoxin (Vc-H-ST) by Vibrio cholerae non-O1 serogroup Hakata was investigated, and the purified Vc-H-ST was characterized. It has a unique amino acid sequence, LIDCCEICCNPACFGCLN. This sequence is quite similar to that of the heat-stable enterotoxin (NAG-ST) produced by V. cholerae non-O1 except for one amino acid (leucine) residue excess at the N terminus. Other characteristics, including biological activity, are compatible with those of NAG-ST.

引用

页码：2186 / 2188

页数：3

共 12 条

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