STRUCTURE OF MALFORMIN-A, A PHYTOTOXIC METABOLITE PRODUCED BY ASPERGILLUS-NIGER

被引：18

作者：

KIM, KW

SUGAWARA, F

YOSHIDA, S

MUROFUSHI, N

TAKAHASHI, N

CURTIS, RW

机构：

[1] INST PHYS & CHEM RES RIKEN, WAKO, SAITAMA 35101, JAPAN

[2] PURDUE UNIV, DEPT BOT & PLANT PATHOL, W LAFAYETTE, IN 47907 USA

[3] UNIV TOKYO, DEPT AGR CHEM, BUNKYO KU, TOKYO 113, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1993年 / 57卷 / 02期

关键词：

D O I：

10.1271/bbb.57.240

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Malformins-produced by Aspergillus niger were separated by HPLC and subjected to structural determination. Amino acid analyses and mass spectra suggested that all of them structurally resembled cyclic pentapeptide malformin A1. Two-dimensional NMR experiments and MS/MS experiments led us to deduce cyclo-D-cysteinyl-D-cysteinyl-L--amino acid-D-amino acid-L-amino acid as being the essential structure of malformins.

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页码：240 / 243

页数：4

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