CHEMICAL SELECTION OF MUTANTS THAT AFFECT ADH ACTIVITY IN DROSOPHILA .3. EFFECTS OF ETHANOL

被引：46

作者：

VIGUE, C ^{[1
]}

SOFER, W ^{[1
]}

机构：

[1] JOHNS HOPKINS UNIV, DEPT BIOL, BALTIMORE, MD 21205 USA

来源：

BIOCHEMICAL GENETICS | 1976年 / 14卷 / 1-2期

关键词：

D O I：

10.1007/BF00484879

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A chemical selection scheme is presented for the isolation of rare Adh-positive Drosophila. It makes use of the fact that flies lacking detectable ADH (alcohol dehydrogenase) activity die as adults or larvae on relatively low concentrations of ethanol in the medium. This procedure is a practical one by crossing 2 Adh-negative alleles, screening 1.5 .times. 106 embryos and isolating 14 Adh-positive survivors.

引用

页码：127 / 135

页数：9

共 10 条

[1] MUTATION IN EUKARYOTES [J].