METHYL 3,4-0-ISOPROPYLIDENE-2-O-(4-METHOXYBENZYL)-1-THIO-BETA-L-FUCOPYRANOSIDE - A NOVEL, EFFICIENT GLYCOSYLATING REAGENT FOR THE SYNTHESIS OF LINEAR AND OTHER ALPHA-L-FUCOSYL OLIGOSACCHARIDES

A facile approach toward the synthesis of linear L-fucosyloligosaccharides containing α-L-(1»2) interglycosidic linkages was made possible through the development and utilization of the titled glycosylating reagent. Synthesis of methyl-O-(α-L-fucopyranosyl)-(lα2)-O(α-L-fucopyranosyl)-(1»2)-α-L-fucopyranoside is described. Extended application toward facile and stereoselective synthesis of fucosyl oligosaccharides containing an anomeric p-nitrophenyl or benzyl group is presented. © 1990.