PREPARATION OF POTENTIALLY BIOACTIVE AZA AND THIAZA POLYCYCLIC COMPOUNDS CONTAINING A BRIDGEHEAD NITROGEN ATOM - SYNTHESIS OF PYRROLO[1,2,3-DE]-1,4-BENZOTHIAZINE DERIVATIVES

被引：5

作者：

ARMENISE, D

TRAPANI, G

ARRIVO, V

MORLACCHI, F

机构：

[1] Dipartimento Farmaco-chimico, Università, Bari, 70126

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1990年 / 27卷 / 06期

关键词：

D O I：

10.1002/jhet.5570270601

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of some pyrrolo[1,2,3‐de]‐1,4‐benzothiazine derivatives by using a modified Bischler type cyclization of N‐(2,2‐diethoxyethyl)‐2H‐1,4‐benzothiazines as a crucial step is described. The alternative approach based on Friedel‐Crafts alkylation of the N‐(2‐chloroethyl)‐2H‐1,4‐benzothiazines is shown to be impractical due to the low yield obtained. Copyright © 1990 Journal of Heterocyclic Chemistry

引用

页码：1521 / 1525

页数：5

共 18 条

[1] SYNTHESIS OF APO-BETA-ERYTHROIDINE [J].