THE INITIATION SITE FOR RECOMBINATION COG IS AT THE 3' END OF THE HIS-3 GENE IN NEUROSPORA-CRASSA

被引：16

作者：

BOWRING, FJ

CATCHESIDE, DEA

机构：

[1] School of Biological Sciences, Flinders University, Bedford Park, 5042, South Australia

来源：

MOLECULAR & GENERAL GENETICS | 1991年 / 229卷 / 02期

关键词：

COG; MEIOSIS; NEUROSPORA-CRASSA; RECOMBINATION; REC-2;

D O I：

10.1007/BF00272166

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recombination at his-3 in Neurospora crassa is thought to be initiated through a site designated cog which lies in the his-3 to ad-3 interval of linkage group I. Fragments of the his-3 gene were used to transform various his-3 mutant alleles to prototrophy in order to link the genetic map to the nucleotide sequence. It was established that cog is at the 3' end of his-3 and is therefore not the his-3 promoter. This suggests that cog may be dissimilar to a number of yeast recombinators which are associated with promoters of transcription.

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收藏

页码：273 / 277

页数：5

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