NEUROTRANSMITTER REGULATION OF ADENOSINE-3',5'-MONOPHOSPHATE IN CLONAL NERVE, GLIA, AND MUSCLE-CELL LINES

被引：63

作者：

SCHUBERT, D ^{[1
]}

TARIKAS, H ^{[1
]}

LACORBIERE, M ^{[1
]}

机构：

[1] SALK INST, DEPT NEUROBIOL, SAN DIEGO, CA 92112 USA

来源：

SCIENCE | 1976年 / 192卷 / 4238期

关键词：

D O I：

10.1126/science.176728

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Norepinephrine increased the intracellular level of cyclic[c]AMP in clonal cell lines of nerve, glia, smooth muscle and skeletal muscle. The largest response was in skeletal muscle, where the cyclic nucleotide concentration was elevated more than 500-fold. Glia and muscle cells, but not nerve cells, responded to dopamine with increased cAMP accumulation. This response appeared to be mediated through a .beta.-adrenoreceptor.

引用

页码：471 / 472

页数：2

共 33 条

[1]

ANDERSSON R, 1972, ADV CYCLIC NUCL PROT, V1, P213

[2] CATECHOLAMINE INDUCED INCREASE OF CYCLIC ADENOSINE 3',5'-MONOPHOSPHATE IN RAT-BRAIN IN-VIVO [J].