TRANSLOCATION (8 13) AND T-CELL LYMPHOMA - A CASE-REPORT

被引：44

作者：

FAGAN, K ^{[1
]}

HYDE, S ^{[1
]}

HARRISON, P ^{[1
]}

机构：

[1] MATER HOSP,WARATAH,NSW,AUSTRALIA

来源：

CANCER GENETICS AND CYTOGENETICS | 1993年 / 65卷 / 01期

关键词：

D O I：

10.1016/0165-4608(93)90062-Q

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A patient with a myeloproliferative disorder is described with an eosinophilia together with T-cell lymphoma. A unique translocation t(8;13)(p11.2;q12) was present in all bone marrow cells examined at presentation. No evidence of this translocation was found in a peripheral blood lymphocyte culture. Chromosome analysis after 9 months revealed this same translocation as well as an extra chromosome 21 in all cells; 4.5% of cells also had an additional chromosome 9. The morphologic diagnosis at this stage was chronic myelomonocytic leukemia. Immunophenotyping 3 months later was consistent with a stem-cell leukemia.

引用

页码：71 / 73

页数：3