Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China

被引：41

作者：

DeSilva, Mary Bachman ^{[1
]}

Gifford, Allen L. ^{[2
]}

Xu Keyi ^{[3
]}

Zhong Li ^{[4
]}

Cheng Feng ^{[5
]}

Brooks, Mohamad ^{[1
]}

Harrold, Mark ^{[1
]}

Hu Yueying ^{[6
]}

Gill, Christopher J. ^{[1
]}

Xie Wubin ^{[4
]}

Vian, Taryn ^{[1
]}

Haberer, Jessica ^{[7
]}

Bangsberg, David ^{[7
]}

Sabin, Lora ^{[1
]}

机构：

[1] Boston Univ, Sch Publ Hlth, Ctr Global Hlth & Dev, 801 Massachusetts Ave,Crosstown,3rd Floor, Boston, MA 02118 USA

[2] Boston Univ, Sch Publ Hlth, Dept Hlth Policy & Management, Boston, MA 02118 USA

[3] Ditan Hosp, 13 Ditan Pk,Andingmen Outer St, Beijing 100011, Peoples R China

[4] FHI 360, Asia Pacif RegionalOffice, 19th Floor,Tower 3,Sindhorn Bldg,130-132Wireless, Bangkok 10330, Thailand

[5] Global Hlth Strategies, Manila Room,17th Floor,Ping Int Financial Plaza,T, Beijing 100022, Peoples R China

[6] Guangxi CDC ART Clin, 18 Jinzhou Rd, Nanning 530028, Peoples R China

[7] Massachusetts Gen Hosp, Ctr Global Hlth, 100 Cambridge St,15th Floor, Boston, MA 02114 USA

来源：

AIDS RESEARCH AND TREATMENT | 2013年 / 2013卷

关键词：

D O I：

10.1155/2013/957862

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We collected data on feasibility and acceptability of a real-time web-linked adherence monitoring container among HIV-positive injection drug users (IDU) in China. "Wisepill" uses wireless technology to track on-time medication dosing. Ten patients on antiretroviral therapy (ART) at the Guangxi CDC HIV clinic in Nanning, China, used Wisepill for one ART medication for one month. We monitored device use and adherence and explored acceptability of the device among patients. Mean adherence was 89.2% (SD 10.6%). Half of the subjects reported a positive overall experience with Wisepill. Seven said that it was inconvenient, supported by comments that it was large and conspicuous. Five worried about disclosure of HIV status due to the device; no disclosures were reported. Twelve signal lapses occurred (5.4% of prescribed doses), of which one was due to technical reasons, nine to behavioral reasons (both intentional and unintentional), and two to unclear reasons. Although the technical components must be monitored carefully, and acceptability to patients presents challenges which warrant further exploration, the Wisepill device has potential for adherence interventions that deliver rapid adherence-support behavioral feedback directly to patients, including IDU. The use of wireless technology appears uniquely promising for providing time-sensitive communication on patient behavior that can be harnessed to maximize the benefits of HIV treatment.

引用

页数：6

共 16 条

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