EVOLUTIONARY RELATIONSHIPS BETWEEN SUGAR KINASES AND TRANSCRIPTIONAL REPRESSORS IN BACTERIA

被引：164

作者：

TITGEMEYER, F ^{[1
]}

REIZER, J ^{[1
]}

REIZER, A ^{[1
]}

SAIER, MH ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO,DEPT BIOL,LA JOLLA,CA 92093

来源：

MICROBIOLOGY-UK | 1994年 / 140卷

关键词：

TRANSCRIPTION; REPRESSORS; SUGAR KINASES; PHYLOGENETIC FAMILY; EVOLUTION;

D O I：

10.1099/13500872-140-9-2349

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We have characterized a new family of proteins (the ROK family) which includes six transcriptional repressors for sugar catabolic operons, three sugar kinases, and three unidentified open reading frames. Analyses of the aligned sequences and phylogenetic tree construction allow predictions regarding the functional nature of conserved domains and residues within these proteins as well as the pathway of evolutionary divergence that gave rise to the family.

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页码：2349 / 2354

页数：6

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