GROWTH-INHIBITORS AGAINST TUMOR-CELLS IN CORDYCEPS SINENSIS OTHER THAN CORDYCEPIN AND POLYSACCHARIDES

被引：80

作者：

KUO, YC

LIN, CY

TSAI, WJ

WU, CL

CHEN, CF

SHIAO, MS

机构：

[1] VET GEN HOSP,DEPT MED RES,LIPID RES LAB,TAIPEI 11217,TAIWAN

[2] VET GEN HOSP,NAT RES INST CHINESE MED,DEPT MED RES,TAIPEI 11217,TAIWAN

来源：

CANCER INVESTIGATION | 1994年 / 12卷 / 06期

关键词：

D O I：

10.3109/07357909409023046

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cordyceps sinensis is a parasitic fungus that has been used as a Chinese medicine for a long time. In the present study, inhibitory effects of crude methanolic extracts of C. sinensis fruiting bodies on various tumor cell lines were demonstrated. The crude methanolic extracts were fractionated into 15 fractions by silica gel column chromatography. Two of the 15 fractions (CS-36-39 and CS-48-51) significantly inhibited the growth of K562, Vero, Wish, Calu-1, and Raji tumor cell lines. The inhibitory activities were not due to the polysaccharides, which have been removed in the extracting process. The polarities of these two fractions indicated that they were different from that of cordycepin. Therefore, it is suggested that tumor cell growth inhibitors, other than cordycepin and polysaccharides, are contained in C. sinensis.

引用

页码：611 / 615

页数：5

共 18 条

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