A CONCISE TOTAL SYNTHESIS OF (+/-)-MAMANUTHAQUINONE BY USING AN EXO-DIELS-ALDER REACTION

被引：57

作者：

YOON, T

DANISHEFSKY, SJ

DEGALA, S

机构：

[1] YALE UNIV,DEPT CHEM,NEW HAVEN,CT 06511

[2] YALE UNIV,CTR CHEM INSTRUMENTAT,NEW HAVEN,CT 06511

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1994年 / 33卷 / 08期

关键词：

D O I：

10.1002/anie.199408531

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Only eight steps are required to synthesize the cytotoxic title compound 1 thanks to the unexpectedly high exo selectivity in the key step. This selectivity can most likely be attributed to steric factors; the diene contains a geminal dimethyl group, the dienophile a bulky aryl group. (Figure Presented.) Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：853 / 855

页数：3

共 23 条

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