SELECTIVITY IN PALLADIUM(0)-CATALYZED CROSS-COUPLING REACTIONS - APPLICATION TO A TANDEM STILLE REACTION

被引：32

作者：

HITCHCOCK, SA

MAYHUGH, DR

GREGORY, GS

机构：

[1] Eli Lilly and Company, Infectious Disease Research Lilly Corporate Center, Indianapolis

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 50期

关键词：

D O I：

10.1016/0040-4039(95)01985-Q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A tandem palladium-catalyzed cross-coupling reaction between a pyridyl triflate 1a and a variety of aryl bromides mediated by hexamethylditin is described The reaction apparently proceeds via the intermediacy of the labile pyridylstannane 1b indicating that the oxidative addition of palladium(0) to the triflate, subsequent transmetalation with hexamethylditin and reductive elimination occurs selectively in the presence of the aryl halide.

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页码：9085 / 9088

页数：4

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