LOCALIZATION OF THE REELER GENE RELATIVE TO FLANKING LOCI ON MOUSE CHROMOSOME-5

被引:10
作者
GOFFINET, AM [1 ]
DERNONCOURT, C [1 ]
机构
[1] FUNPD,SCH MED,DEPT PHYSIOL,B-5000 NAMUR,BELGIUM
关键词
D O I
10.1007/BF02443785
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The location of the reeler (rl) locus in mice in the paracentromeric part of chromosome (Chr) 5, proximal to the T(5;12)31H translocation breakpoint, has been confirmed. Analysis of DNA from animals with different doses of the proximal part of Chr 5 and from congenic mice showed that the Pgy-1 locus is the closest marker to rl, whereas En-2 is located farther, distal to the T31H breakpoint. Together with recently published evidence (Martin et al. 1989), our data suggest the following order: Cen-rl/Pgy-1-T31H-En-2.
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页码:100 / 103
页数:4
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