THYROID-HORMONE STIMULATES PHOSPHOGLYCERATE MUTASE ACTIVITY AND ISOZYME TRANSITION IN RAT MUSCLE TISSUES

被引：7

作者：

ESTELLER, M

URENA, J

CARRERAS, J

MARTELLY, I

CLIMENT, F

机构：

[1] UNIV BARCELONA, FAC MED, UNITAT BIOQUIM, E-08036 BARCELONA, SPAIN

[2] UNIV PARIS 12, UFR SCI & TECHNOL, MYREM, CRETEIL, FRANCE

来源：

LIFE SCIENCES | 1994年 / 54卷 / 08期

关键词：

D O I：

10.1016/0024-3205(94)90003-5

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Triiodothyronine (T3) increases phosphoglycerate mutase (PGAM) specific activity in rat skeletal and cardiac muscles. This increase is concomitant with an increase in the proportion of phosphoglycerate mutase isozymes which contain type-M subunit. Propylthiouracil (PTU), an anti-hormone, not only decreases phosphoglycerate mutase activity with respect to control rats, but also decreases the total M subunit contents. In liver, which only possesses type-B subunit phosphoglycerate mutase, none of the effects were detected.

引用

页码：533 / 538

页数：6

共 28 条

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