COMPARATIVE NEUROIMAGING WITH PATHOLOGICAL CORRELATES IN ALEXANDERS DISEASE

被引:15
作者
HESS, DC [1 ]
FISCHER, AQ [1 ]
YAGHMAI, F [1 ]
FIGUEROA, R [1 ]
AKAMATSU, Y [1 ]
机构
[1] MED COLL GEORGIA,DEPT RADIOL,AUGUSTA,GA 30912
关键词
D O I
10.1177/088307389000500320
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We describe a case of pathologically confirmed Alexander's disease in which serial cranial ultrasound studies demonstrated unique findings of enlarging subependymal cysts with evolving periventricular hyperechogenicity. Computed tomographic scan of the head showed low attenuation of the periventricular white matter and centrum semiovale. Magnetic resonance imaging (MRI) demonstrated diffuse, confluent high signal predominantly in frontal white matter. These imaging modalities, particularly cranial ultrasound and MRI, may be useful tools in the diagnostic evaluation of children with degenerative neurologic disease, megalencephaly, and suspected Alexander's disease. (J Child Neurol 1990;5:248-252). © 1990, Sage Publications. All rights reserved.
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页码:248 / 252
页数:5
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