NUCLEOTIDE AND DEDUCED AMINO-ACID-SEQUENCES OF THE GENE ENCODING VIRION PROTEIN-16 OF HERPES-SIMPLEX VIRUS TYPE-2

被引：22

作者：

CRESS, A ^{[1
]}

TRIEZENBERG, SJ ^{[1
]}

机构：

[1] MICHIGAN STATE UNIV,DEPT BIOCHEM,E LANSING,MI 48824

来源：

GENE | 1991年 / 103卷 / 02期

关键词：

RECOMBINANT DNA; TRANSCRIPTION ACTIVATION; VP16; IMMEDIATE-EARLY GENE INDUCTION; ACIDIC ACTIVATING DOMAIN; HOMOLOGY;

D O I：

10.1016/0378-1119(91)90278-J

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A virion protein (VP16) of herpes simplex virus (HSV) activates transcription of viral immediate-early genes. We have determined the nucleotide sequence of the virion activator gene from HSV-2, which we term VP16-2. Comparison of the deduced amino acid sequences of the HSV-1 and HSV-2 homologs shows that the VP16-2 gene product retains features determined to be important for transcriptional activation by VP16.

引用

页码：235 / 238

页数：4

共 25 条

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