DETERMINATION OF THE SERUM CONCENTRATION OF SPIRONOLACTONE AND ITS METABOLITES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：29

作者：

OVERDIEK, JWPM ^{[1
]}

HERMENS, WAJJ ^{[1
]}

MERKUS, FWHM ^{[1
]}

机构：

[1] UNIV AMSTERDAM,BIOPHARMACEUT LAB,1018 TV AMSTERDAM,NETHERLANDS

来源：

JOURNAL OF CHROMATOGRAPHY | 1985年 / 341卷 / 02期

关键词：

D O I：

10.1016/S0378-4347(00)84041-4

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

引用

页码：279 / 285

页数：7

共 18 条

[1] KINETICS OF CANRENONE AFTER SINGLE AND MULTIPLE DOSES OF SPIRONOLACTONE [J].

ABSHAGEN, U ;

BESENFELDER, E ;

ENDELE, R ;

KOCH, K ;

NEUBERT, B .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1979, 16 (04) :255-262

[2]

ABSHAGEN U, 1976, N-S ARCH PHARMACOL, V296, P37, DOI 10.1007/BF00498838

[3]

BESENFELDER E, 1981, Journal of High Resolution Chromatography and Chromatography Communications, V4, P419, DOI 10.1002/jhrc.1240040814

[4]

DAHLOF CG, 1979, DRUG METAB DISPOS, V7, P103

[5]

GOCHMAN N, 1962, J PHARMACOL EXP THER, V135, P312

[6] SPIRONOLACTONE - DIVERSITY IN METABOLIC PATHWAYS [J].

KARIM, A ;

HRIBAR, J ;

DOHERTY, M ;

AKSAMIT, W ;

CHAPPELOW, D ;

BROWN, E ;

MARKOS, C ;

CHINN, LJ ;

LIANG, D ;

ZAGARELLA, J .

XENOBIOTICA, 1977, 7 (10) :585-600

[7] ISOLATION AND IDENTIFICATION OF NOVEL SULFUR-CONTAINING METABOLITES OF SPIRONOLACTONE (ALDACTONE-R) [J].

KARIM, A ;

BROWN, EA .

STEROIDS, 1972, 20 (01) :41-&

[8]

KARIM A, 1976, CLIN PHARMACOL THER, V19, P158

[9] DETERMINATION OF CANRENONE, THE MAJOR METABOLITE OF SPIRONOLACTONE, IN PLASMA AND URINE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

KRAUSE, W ;

KARRAS, J ;

JAKOBS, U .

JOURNAL OF CHROMATOGRAPHY, 1983, 277 (OCT) :191-199

[10]

MELANDER A, 1977, CLIN PHARMACOL THER, V22, P100

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