SPASMOLYTIC FLAVONOLS FROM ARTEMISIA-ABROTANUM

被引：27

作者：

BERGENDORFF, O ^{[1
]}

STERNER, O ^{[1
]}

机构：

[1] LUND UNIV, DIV ORGAN CHEM 2, S-22100 LUND, SWEDEN

来源：

PLANTA MEDICA | 1995年 / 61卷 / 04期

关键词：

D O I：

10.1055/s-2006-958106

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four flavonols with spasmolytic activity have been isolated from a methanol extract of Artemisia abrotanum L. (Asteraceae), as the principles primarily responsible for the smooth muscle relaxing activity of this plant. The flavonols show a dose-dependent relaxing effect on the carbacholine-induced contraction of guinea-pig trachea, the EC(50) values for compounds 1-3 are 20-30 mu mol/l while compound 4 is less active.

引用

页码：370 / 371

页数：2