CONTACT SENSITIVITY TO CHLORHEXIDINE

被引：23

作者：

BECHGAARD, E ^{[1
]}

PLOUG, E ^{[1
]}

HJORTH, N ^{[1
]}

机构：

[1] GENTOFTE HOSP, DEPT DERMATOL, DK-2900 COPENHAGEN, DENMARK

来源：

CONTACT DERMATITIS | 1985年 / 13卷 / 02期

关键词：

D O I：

10.1111/j.1600-0536.1985.tb02504.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

In a joint study, 2061 patients (1346 women and 715 men) were patch tested with chlorhexidine gluconate 1% in water, included in a standard test series. 48 patients (2.3%) showed a positive reaction. These were relatively more common in men (3.2%) than in women (1.9%). Positive reactions were most common in patients with leg eczema (6.8%) or leg ulcer (10.9%). Of the 48 patients who were patch test positive, 14 (2 with leg ulcer) were retested with chlorhexidine gluconate 0.01 and 1%. Only one with a leg ulcer was positive. These findings indicate that false positive reactions, known as "the excited skin syndrome", may arise from testing eczema patients in a standard series. The sensitizing potential of chlorhexidine may be very low, but the potential in patients with an eczema or ulcer of the leg has to be further evaluated.

引用

页码：53 / 55

页数：3