STIMULATION OF THE PITUITARY-ADRENAL AXIS WITH ARGININE VASOPRESSIN IN PATIENTS WITH DEPRESSION

被引：16

作者：

MELLER, WH

KATHOL, RC

JAECKLE, RS

LOPEZ, JF

机构：

[1] UNIV IOWA HOSP & CLIN, DEPT INTERNAL MED, IOWA CITY, IA 52242 USA

[2] UNIV MICHIGAN, MED CTR, MENTAL HLTH RES INST, ANN ARBOR, MI 48109 USA

来源：

JOURNAL OF PSYCHIATRIC RESEARCH | 1987年 / 21卷 / 03期

关键词：

D O I：

10.1016/0022-3956(87)90028-8

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The ACTH response to arginine vasopressin was the same in patients with depression while cortisol response was significantly greater in patients with depression when compared to the control population. These findings are consistent with the hypothesis that vasopressin corticotroph receptors are not downregulated in depression and that there is increased adrenal responsiveness in patients with depression to endogenous ACTH.

引用

页码：269 / 277

页数：9

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