HYBRIDIZATION OF ALTERNATING CATIONIC/ANIONIC OLIGONUCLEOTIDES TO RNA SEGMENTS

被引：28

作者：

JUNG, PM ^{[1
]}

HISTAND, G ^{[1
]}

LETSINGER, RL ^{[1
]}

机构：

[1] NORTHWESTERN UNIV,DEPT CHEM,EVANSTON,IL 60208

来源：

NUCLEOSIDES & NUCLEOTIDES | 1994年 / 13卷 / 6-7期

关键词：

D O I：

10.1080/15257779408012174

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

It is shown that oligonucleotide analogues containing alternating phosphodiester groups and cationic groups linked to phosphorus through an amidate bond hybridize to complementary RNA segments. An improved synthetic procedure for the alternating compounds is also described.

引用

页码：1597 / 1605

页数：9

共 8 条

[1] ZWITTERIONIC DNA [J].