SOLID-PHASE SYNTHESIS OF OLIGORIBONUCLEOTIDES USING 9-FLUORENYLMETHOXYCARBONYL (FMOC) FOR 5'-HYDROXYL PROTECTION

被引：63

作者：

LEHMANN, C ^{[1
]}

XU, YZ ^{[1
]}

CHRISTODOULOU, C ^{[1
]}

TAN, ZK ^{[1
]}

GAIT, MJ ^{[1
]}

机构：

[1] MRC,MOLEC BIOL LAB,HILLS RD,CAMBRIDGE CB2 2QH,ENGLAND

来源：

NUCLEIC ACIDS RESEARCH | 1989年 / 17卷 / 07期

关键词：

D O I：

10.1093/nar/17.7.2379

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：2379 / 2390

页数：12

共 30 条

[1] SOLID-PHASE SYNTHESIS OF DNA UNDER A NON-DEPURINATING CONDITION WITH A BASE LABILE 5'-PROTECTING GROUP (FMOC) USING PHOSPHITEAMIDITE APPROACH [J].

BALGOBIN, N ;

CHATTOPADHYAYA, J .

NUCLEOSIDES & NUCLEOTIDES, 1987, 6 (1-2) :461-463

[2] INCOMPATIBILITY OF ACID-LABILE 2' AND 5' PROTECTING GROUPS FOR SOLID-PHASE SYNTHESIS OF OLIGORIBONUCLEOTIDES [J].

CHRISTODOULOU, C ;

AGRAWAL, S ;

GAIT, MJ .

TETRAHEDRON LETTERS, 1986, 27 (13) :1521-1522

[3] A NEW 5'-PROTECTING GROUP FOR USE IN SOLID-PHASE SYNTHESIS OF OLIGORIBONUCLEOTIDES [J].

CHRISTODOULOU, C ;

AGRAWAL, S ;

GAIT, MJ .

NUCLEOSIDES & NUCLEOTIDES, 1987, 6 (1-2) :341-344

[4]

CHRISTODOULOU C, 1987, BIOPHOSPHATES THEIR, P99

[5] AN IMPROVED SYNTHESIS OF 5-SUBSTITUTED TETRAZOLES [J].

FINNEGAN, WG ;

HENRY, RA ;

LOFQUIST, R .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1958, 80 (15) :3908-3911

[6] SUBSTITUTED 5-PHENYLTETRAZOLES - IMPROVED ACTIVATORS OF DEOXYNUCLEOSIDE PHOSPHORAMIDITES IN DEOXYOLIGONUCLEOTIDE SYNTHESIS [J].

FROEHLER, BC ;

MATTEUCCI, MD .

TETRAHEDRON LETTERS, 1983, 24 (31) :3171-3174

[7]

FUKUDA T, 1988, NUCLEIC ACIDS RES S, V19, P13

[8]

Gait M. J, 1984, OLIGONUCLEOTIDE SYNT

[9] THE FLUOREN-9-YLMETHOXYCARBONYL GROUP FOR THE PROTECTION OF HYDROXY-GROUPS - ITS APPLICATION IN THE SYNTHESIS OF AN OCTATHYMIDYLIC ACID FRAGMENT [J].

GIOELI, C ;

CHATTOPADHYAYA, JB .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1982, (12) :672-674

[10]

GRIFFIN BE, 1964, TETRAHEDRON LETT, P2925

← 1 2 3 →