FORCED MIDEXPIRATORY TIME - REFERENCE VALUES AND THE EFFECT OF CIGARETTE-SMOKING

被引：3

作者：

BROWN, LK

MILLER, A

PILIPSKI, M

LAU, TS

机构：

[1] MT SINAI MED CTR,DEPT MED,DIV PULM & CRIT CARE MED,NEW YORK,NY 10029

[2] MT SINAI MED CTR,DEPT BIOMATH SCI,NEW YORK,NY 10029

来源：

LUNG | 1995年 / 173卷 / 01期

关键词：

MAXIMAL EXPIRATORY FLOW-VOLUME CURVES; MAXIMAL MIDEXPIRATORY FLOW RATE; RESPIRATORY FUNCTION TESTS; AIRWAY OBSTRUCTION; LUNG DISEASES; OBSTRUCTIVE;

D O I：

暂无

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Background: Forced midexpiratory time (FET(25-75%)), the time required to exhale from 25 to 75% of forced vital capacity (FVC), has been advocated as a relatively volume-independent measure of obstruction. Previous estimates of normal FET(25-75%) have not systematically studied the effect of age, height, sex, and smoking history. Methods: We analyzed flow-volume loops from 369 normal lifetime nonsmokers and smokers, a random sample of the population of Michigan. Linear models including age and/or height were considered, with and without logarithmic transformation. Results: The best models used age, or age and height, and no transformation. Age and height contributed much less to the variability of FET(25-75%) than to spirometric flows previously investigated. The Largest r(2) was found in the male smokers, with the largest contribution from age, suggesting a smoking effect. Conclusions: As age was the major contributor to the value of FET(25-75%) and that contribution was small, we suggest the use of simplified age-stratified reference values derived from our data.

引用

页码：35 / 46

页数：12

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