PRIMARY STRUCTURE OF CAMP-GATED CHANNEL FROM BOVINE OLFACTORY EPITHELIUM

被引:203
作者
LUDWIG, J
MARGALIT, T
EISMANN, E
LANCET, D
KAUPP, UB
机构
[1] FORSCHUNGSZENTRUM JULICH, INST BIOL INFORMAT VERARBEITUNG, POSTFACH 1913, W-5170 JULICH, GERMANY
[2] WEIZMANN INST SCI, DEPT MEMBRANE RES, IL-76100 REHOVOT, ISRAEL
来源
FEBS LETTERS | 1990年 / 270卷 / 1-2期
关键词
cAMP-gated channel; cDNA cloning; Olfactory epithelium; Signal transduction;
D O I
10.1016/0014-5793(90)81226-E
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The complete amino-acid sequence of the bovine olfactory epithelium adenosine 3',5'cyclic monophosphate (cAMP)-gated channel has been determined by cloning and sequencing its cDNA. It exhibits a high degree of sequence homology with the cGMP-gated channel of rod photoreceptors, suggesting that cyclic nucleotide-gated channels fall into a new family of genetically related proteins. © 1990.
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页码:24 / 29
页数:6
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