RENIN SYSTEM BLOCKADE AS A THERAPEUTIC STRATEGY - PAST, PRESENT, AND FUTURE

[1] Goldblatt H., Katz Y.J., Lewis H.A., Richardson E., Studies on experimental hypertension. Production of persistentelevation of systolic blood pressure by means of renal ischemia, J Exp Med, 59, pp. 347-349, (1934)

[2] Laragh J.H., The role of aldosterone in man: Evidence for regulation of electrolyte balance and arterial pressure by a renal-adrenal system which may be involved in malignant hypertension, JAMA, 174, pp. 293-295, (1960)

[3] Laragh J.H., Ledingham J., Sommers S.C., Secondary aldosteronism and reduced plasma renin in hypertensive disease, Trans Assoc am Physicians, 80, pp. 168-182, (1967)

[4] Laragh J.H., Baer L., Brunner H.R., Et al., Renin, angiotensin and aldosterone system in pathogenesis and management of hypertensive vascular disease, Am J Med, 52, pp. 633-652, (1972)

[5] Brunner H.R., Laragh J.H., Baer L., Et al., Essential hypertension: Renin and aldosterone, heart attack and stroke, N Engl J Med, 286, pp. 441-449, (1972)

[6] Gavras H., Brunner H.R., Vaughan E.D., Laragh J.H., Angiotensin-sodium interaction in blood pressure maintenance of renal hypertensive and normotensive rats, Science, 180, pp. 1369-1372, (1973)

[7] Buhler H.R., Laragh H., Baer L., Et al., Propranolol inhibition of renin secretion. A specific approach to diagnosis and treatment of renin-dependent hypertensive diseases, N Engl J Med, 187, pp. 1209-1214, (1972)

[8] Dray Er J., Keim H.R., Weber H., Et al., Unexpected pressor responses to propranolol in essential hypertension, Am J Med, 60, pp. 897-903, (1976)

[9] Brunner H.R., Gavras H., Laragh J.H., Keenan R., Hypertension in man. Exposure of the renin and sodium components using angiotensin II blockade, Circ Res, 34, pp. 35-43, (1974)

[10] Streeten D., Erson G.H., Dalakos T.G., Angiotensin blockade: Its clinical significance, Am J Med, 60, pp. 817-824, (1976)

[1] Goldblatt H., Katz Y.J., Lewis H.A., Richardson E., Studies on experimental hypertension. Production of persistentelevation of systolic blood pressure by means of renal ischemia, J Exp Med, 59, pp. 347-349, (1934)

[2] Laragh J.H., The role of aldosterone in man: Evidence for regulation of electrolyte balance and arterial pressure by a renal-adrenal system which may be involved in malignant hypertension, JAMA, 174, pp. 293-295, (1960)

[3] Laragh J.H., Ledingham J., Sommers S.C., Secondary aldosteronism and reduced plasma renin in hypertensive disease, Trans Assoc am Physicians, 80, pp. 168-182, (1967)

[4] Laragh J.H., Baer L., Brunner H.R., Et al., Renin, angiotensin and aldosterone system in pathogenesis and management of hypertensive vascular disease, Am J Med, 52, pp. 633-652, (1972)

[5] Brunner H.R., Laragh J.H., Baer L., Et al., Essential hypertension: Renin and aldosterone, heart attack and stroke, N Engl J Med, 286, pp. 441-449, (1972)

[6] Gavras H., Brunner H.R., Vaughan E.D., Laragh J.H., Angiotensin-sodium interaction in blood pressure maintenance of renal hypertensive and normotensive rats, Science, 180, pp. 1369-1372, (1973)

[7] Buhler H.R., Laragh H., Baer L., Et al., Propranolol inhibition of renin secretion. A specific approach to diagnosis and treatment of renin-dependent hypertensive diseases, N Engl J Med, 187, pp. 1209-1214, (1972)

[8] Dray Er J., Keim H.R., Weber H., Et al., Unexpected pressor responses to propranolol in essential hypertension, Am J Med, 60, pp. 897-903, (1976)

[9] Brunner H.R., Gavras H., Laragh J.H., Keenan R., Hypertension in man. Exposure of the renin and sodium components using angiotensin II blockade, Circ Res, 34, pp. 35-43, (1974)

[10] Streeten D., Erson G.H., Dalakos T.G., Angiotensin blockade: Its clinical significance, Am J Med, 60, pp. 817-824, (1976)