PLATELET SIZE IN HEALTH AND HEMATOLOGIC DISEASE

被引:92
作者
BESSMAN, JD
WILLIAMS, LJ
GILMER, PR
机构
[1] UNIV TEXAS, MED BRANCH, DEPT MED, GALVESTON, TX 77550 USA
[2] UNIV TEXAS, MED BRANCH, DEPT PATHOL, GALVESTON, TX 77550 USA
[3] UNIV TEXAS, MED BRANCH, HEMATOL AUTOMAT LAB, GALVESTON, TX 77550 USA
关键词
D O I
10.1093/ajcp/78.2.150
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
In normal [human] subjects, mean platelet volume (MPV) has an inverse, nonlinear relation with platelet count, while platelet volume heterogeneity has a direct, nonlinear relation with MPV. Compared with the reference range established for normal subjects, patients with chronic lymphocytic leukemia, atherosclerotic heart disease, diabetes mellitus and chronic undifferentiated schizophrenia had normal mean platelet volume and heterogeneity. Patients treated with cytotoxic chemotherapy for acute nonlymphocytic leukemia, patients with megaloblastic anemia and patients with aplastic anemia had abnormally small platelets with increased heterogeneity. Patients with chronic myelogenous leukemia had abnormally large platelets with increased heterogeneity.
引用
收藏
页码:150 / 153
页数:4
相关论文
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