SPECIES VARIATION IN THE METABOLIC-ACTIVATION OF PARACETAMOL TO TOXIC INTERMEDIATES - ROLE OF CYTOCHROME-P-450 AND CYTOCHROME-P-448

被引：43

作者：

IOANNIDES, C

STEELE, CM

PARKE, DV

机构：

来源：

TOXICOLOGY LETTERS | 1983年 / 16卷 / 1-2期

关键词：

D O I：

10.1016/0378-4274(83)90010-3

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

引用

页码：55 / 61

页数：7

共 27 条

[1] PARACETAMOL OXIDATION - SYNTHESIS AND REACTIVITY OF N-ACETYL-P-BENZOQUINONEIMINE [J].

BLAIR, IA ;

BOOBIS, AR ;

DAVIES, DS ;

CRESP, TM .

TETRAHEDRON LETTERS, 1980, 21 (51) :4947-4950

[2] LIVER NECROSIS FROM PARACETAMOL [J].

BOYD, EM ;

BERECZKY, GM .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1966, 26 (03) :606-&

[3] ACUTE LIVER NECROSIS FOLLOWING OVERDOSE OF PARACETAMOL [J].

DAVIDSON, DG ;

EASTHAM, WN .

BRITISH MEDICAL JOURNAL, 1966, 2 (5512) :497-&

[4] SPECIES-DIFFERENCES IN HEPATIC GLUTATHIONE DEPLETION, COVALENT BINDING AND HEPATIC NECROSIS AFTER ACETAMINOPHEN [J].

DAVIS, DC ;

POTTER, WZ ;

JOLLOW, DJ ;

MITCHELL, JR .

LIFE SCIENCES, 1974, 14 (11) :2099-2109

[5] INHIBITION OF CYTOCHROME P-448 MIXED-FUNCTION OXIDASE ACTIVITY FOLLOWING ADMINISTRATION OF 9-HYDROXYELLIPTICINE TO RATS [J].

DELAFORGE, M ;

IOANNIDES, C ;

PARKE, DV .

CHEMICO-BIOLOGICAL INTERACTIONS, 1980, 32 (1-2) :101-110

[6]

GEMBORYS MW, 1981, DRUG METAB DISPOS, V9, P340

[7] STUDIES ON THE MECHANISM OF HEPATIC MICROSOMAL N-OXIDE FORMATION - N-OXIDATION OF NN-DIMETHYLANILINE BY A RECONSTITUTED RABBIT LIVER MICROSOMAL CYTOCHROME P-448 ENZYME-SYSTEM [J].

HLAVICA, P ;

HULSMANN, S .

BIOCHEMICAL JOURNAL, 1979, 182 (01) :109-116

[8] MECHANISM OF INDUCTION OF HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYMES BY A SERIES OF BARBITURATES [J].

IOANNIDES, C ;

PARKE, DV .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1975, 27 (10) :739-746

[9] ACTIVATION OF BENZO(A)PYRENE AND 2-ACETAMIDOFLUORENE TO MUTAGENS BY MICROSOMAL PREPARATIONS FROM DIFFERENT ANIMAL SPECIES - ROLE OF CYTOCHROME-P-450 AND P-448 [J].

IOANNIDES, C ;

PARKINSON, C ;

PARKE, DV .

XENOBIOTICA, 1981, 11 (10) :701-708

[10]

JOLLOW DJ, 1973, J PHARMACOL EXP THER, V187, P195

← 1 2 3 →