IMMOBILIZED IODOSOBENZOATE CATALYSTS FOR THE CLEAVAGE OF REACTIVE PHOSPHATES

Titanium dioxide and nylon covalently supported iodosobenzoate reagents 11 and 19 have been prepared by the procedures outlined in Schemes I and II. Both 11 and 19 are good catalysts for the cleavage of p-nitrophenyl diphenyl phosphate (PNPDPP) under heterogeneous aqueous conditions at pH 8. The kinetics of the cleavage reactions have been characterized in the presence of excess substrate (turnover conditions), and in the presence of dilute cetyltrimethylammonium chloride, which enhances both PNPDPP cleavage and catalyst turnover. © 1990, American Chemical Society. All rights reserved.