LIQUID-CHROMATOGRAPHIC SEPARATION OF THE ENANTIOMERS OF DINITROPHENYL AMINO-ACIDS USING A BETA-CYCLODEXTRIN-BONDED STATIONARY PHASE

被引：35

作者：

LI, S ^{[1
]}

PURDY, WC ^{[1
]}

机构：

[1] MCGILL UNIV,DEPT CHEM,801 SHERBROOKE ST W,MONTREAL H3A 2K6,QUEBEC,CANADA

来源：

JOURNAL OF CHROMATOGRAPHY | 1991年 / 543卷 / 01期

关键词：

D O I：

10.1016/S0021-9673(01)95758-9

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A beta-cyclodextrin-bonded chiral stationary phase was used for the liquid chromatographic resolution of racemic amino acid derivatives. Ten pairs of dinitrophenyl amino acid enantiomers were separated by this technique. Methanol-triethylammonium buffer solutions were used as the mobile phases. The effects of pH, methanol and triethylammonium acetate buffer concentration in the mobile phase, and the structural features of the solutes on the retention and enantio-selectivity were examined and discussed in terms of the overall retention mechanism.

引用

页码：105 / 112

页数：8

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