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THE CARDIOVASCULAR EFFECTS OF COCAINE

被引：99
作者：
GOLDFRANK, LR
HOFFMAN, RS
机构：
[1] Emergency Medical Services, Bellevue Hospital, New York University Medical Center, New York City
[2] New York City Poison Control Center, New York City
来源：
ANNALS OF EMERGENCY MEDICINE | 1991年 / 20卷 / 02期
关键词：
COCAINE; CARDIOVASCULAR SYSTEM;
D O I：
10.1016/S0196-0644(05)81217-X
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Cocaine use and abuse continue to overwhelm urban economic, social, and health care systems. Patients frequently present to the emergency department with life-threatening manifestations of cocaine use, including trauma, acquired immune deficiency syndrome, psychomotor agitation, and cardiovascular collapse. Adequate treatment of the cocaine-intoxicated patient requires a critical understanding of the risk-to-benefit ratios for pharmacologic, toxicologic, and surgical or obstetric interventions. The pharmacologic and physiologic bases for the vascular manifestations of cocaine toxicity and experimental evidence for treatment strategies are reviewed.
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页码：165 / 175
页数：11
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