SYNTHESIS OF NOVEL SUBSTITUTED SPIROHYDANTOINS

被引：14

作者：

CARRERA, GM

GARVEY, DS

机构：

[1] Department 47W, Pharmaceutical Discovery Division, Abbott Laboratories, Illinois, 60064, Abbott Park

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1992年 / 29卷 / 04期

关键词：

D O I：

10.1002/jhet.5570290430

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of novel N-1-alkylspirohydantoins (1-alkyl-1,3,8-triazaspiro[4.5]decanes) is reported. The key hydantoin intermediates 3 were prepared using standard hydantoin methodology. This synthesis allows for differential substitution of all three nitrogens.

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页码：847 / 850

页数：4

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