3'-AZIDO-3'-DEOXYTHYMIDINE TRIPHOSPHATE AS AN INHIBITOR AND SUBSTRATE OF PURIFIED HUMAN-IMMUNODEFICIENCY-VIRUS REVERSE-TRANSCRIPTASE

被引：293

作者：

STCLAIR, MH

RICHARDS, CA

SPECTOR, T

WEINHOLD, KJ

MILLER, WH

LANGLOIS, AJ

FURMAN, PA

机构：

[1] BURROUGHS WELLCOME CO,DEPT MICROBIOL,RES TRIANGLE PK,NC 27709

[2] BURROUGHS WELLCOME CO,DEPT EXPTL THERAPY,RES TRIANGLE PK,NC 27709

[3] DUKE UNIV,DEPT SURG,DURHAM,NC 27710

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1987年 / 31卷 / 12期

关键词：

D O I：

10.1128/AAC.31.12.1972

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

引用

页码：1972 / 1977

页数：6

共 24 条

[1] PURIFICATION, CHARACTERIZATION, AND COMPARISON OF DNA POLYMERASES FROM 2 PRIMATE RNA TUMOR-VIRUSES [J].

ABRELL, JW ;

GALLO, RC .

JOURNAL OF VIROLOGY, 1973, 12 (03) :431-439

[2] KINETICS AND INTERMEDIATES IN INTRACELLULAR SYNTHESIS OF BACTERIOPHAGE T4 DEOXYRIBONUCLEIC ACID [J].

ALTMAN, S ;

LERMAN, LS .

JOURNAL OF MOLECULAR BIOLOGY, 1970, 50 (02) :235-&

[3] ISOLATION OF A T-LYMPHOTROPIC RETROVIRUS FROM A PATIENT AT RISK FOR ACQUIRED IMMUNE-DEFICIENCY SYNDROME (AIDS) [J].

BARRESINOUSSI, F ;

CHERMANN, JC ;

REY, F ;

NUGEYRE, MT ;

CHAMARET, S ;

GRUEST, J ;

DAUGUET, C ;

AXLERBLIN, C ;

VEZINETBRUN, F ;

ROUZIOUX, C ;

ROZENBAUM, W ;

MONTAGNIER, L .

SCIENCE, 1983, 220 (4599) :868-871

[4]

BIRON KK, 1984, HERPESVIRUS, P677

[5]

CHENG YC, 1987, J BIOL CHEM, V262, P2187

[6] COMPUTER PROGRAMMES FOR PROCESSING ENZYME KINETIC DATA [J].

CLELAND, WW .

NATURE, 1963, 198 (487) :463-+

[7] ANTIBACTERIAL ACTIVITY AND MECHANISM OF ACTION OF 3'-AZIDO-3'-DEOXYTHYMIDINE (BW-A509U) [J].

ELWELL, LP ;

FERONE, R ;

FREEMAN, GA ;

FYFE, JA ;

HILL, JA ;

RAY, PH ;

RICHARDS, CA ;

SINGER, SC ;

KNICK, VB ;

RIDEOUT, JL ;

ZIMMERMAN, TP .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1987, 31 (02) :274-280

[8] DIFFERENT PATTERNS OF INHIBITION OF AVIAN-MYELOBLASTOSIS VIRUS REVERSE-TRANSCRIPTASE ACTIVITY BY 3'-AZIDO-3'-DEOXYTHYMIDINE 5'-TRIPHOSPHATE AND ITS THREO ISOMER [J].

ERIKSSON, B ;

VRANG, L ;

BAZIN, H ;

CHATTOPADHYAYA, J ;

OBERG, B .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1987, 31 (04) :600-604

[9] EXPRESSION AND PROCESSING OF THE AIDS VIRUS REVERSE-TRANSCRIPTASE IN ESCHERICHIA-COLI [J].

FARMERIE, WG ;

LOEB, DD ;

CASAVANT, NC ;

HUTCHISON, CA ;

EDGELL, MH ;

SWANSTROM, R .

SCIENCE, 1987, 236 (4799) :305-308

[10] INHIBITION OF HERPES-SIMPLEX VIRUS-INDUCED DNA-POLYMERASE ACTIVITY AND VIRAL-DNA REPLICATION BY 9-(2-HYDROXYETHOXYMETHYL)GUANINE AND ITS TRIPHOSPHATE [J].

FURMAN, PA ;

STCLAIR, MH ;

FYFE, JA ;

RIDEOUT, JL ;

KELLER, PM ;

ELION, GB .

JOURNAL OF VIROLOGY, 1979, 32 (01) :72-77

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