DNA DAMAGE-INDUCIBLE LOCI IN SALMONELLA-TYPHIMURIUM

被引：12

作者：

SMITH, CM

ARANY, Z

ORREGO, C

EISENSTADT, E

机构：

[1] HARVARD UNIV,SCH PUBL HLTH,DEPT CANC BIOL,BOSTON,MA 02115

[2] HARVARD UNIV,SCH PUBL HLTH,INTERDISCIPLINARY PROGRAMS PUBL HLTH,BOSTON,MA 02115

来源：

JOURNAL OF BACTERIOLOGY | 1991年 / 173卷 / 11期

关键词：

D O I：

10.1128/jb.173.11.3587-3590.1991

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

lac operon fusions to DNA damage-inducible (din) loci were generated in Salmonella typhimurium LT2. Many of these din fusions were efficiently repressed by cloned Escherichia coli LexA, while others were not; all required RecA for induction. Several din fusions exhibited strong inducibility and will be useful in developing an SOS induction assay in S. typhimurium to detect genotoxins.

引用

页码：3587 / 3590

页数：4

共 27 条

[1] IMPROVED BACTERIAL TEST SYSTEM FOR DETECTION AND CLASSIFICATION OF MUTAGENS AND CARCINOGENS [J].