DETERMINATION OF IMIPENEM IN HUMAN PLASMA, URINE AND TISSUE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：22

作者：

CARLUCCI, G

BIORDI, L

VICENTINI, C

BOLOGNA, M

机构：

[1] UNIV LAQUILA,DIPARTIMENTO MED SPERIMENTALE,CATTEDRA PATOL GEN,I-67100 LAQUILA,ITALY

[2] UNIV LAQUILA,DIPARTIMENTO DISCIPLINE CHIRURG,CATTEDRA CLIN UROL,I-67100 LAQUILA,ITALY

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1990年 / 8卷 / 03期

关键词：

beta-lactam antibiotics; carbapenams; HPLC biological fluids; Imipenem;

D O I：

10.1016/0731-7085(90)80038-Q

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A simple and reliable HPLC method is described for the new beta-lactam antibiotic imipenem; suitable extraction procedures for the drug in human plasma, urine and prostatic tissue are described. The figures of merit for the assays are reported and examples given of their application. © 1990.

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页码：283 / 286

页数：4

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