IDENTIFICATION OF THE ANCESTRAL HAPLOTYPE FOR APOLIPOPROTEIN-B SUGGESTS AN AFRICAN ORIGIN OF HOMO-SAPIENS SAPIENS AND TRACES THEIR SUBSEQUENT MIGRATION TO EUROPE AND THE PACIFIC

被引：20

作者：

RAPACZ, J

CHEN, L

BUTLERBRUNNER, E

WU, MJ

HASLERRAPACZ, JO

BUTLER, R

SCHUMAKER, VN

机构：

[1] UNIV WISCONSIN,DEPT MEAT & ANIM SCI,MADISON,WI 53706

[2] UNIV CALIF LOS ANGELES,DEPT CHEM & BIOCHEM,LOS ANGELES,CA 90024

[3] UNIV CALIF LOS ANGELES,INST MOLEC BIOL,LOS ANGELES,CA 90024

[4] SWISS RED CROSS,BLOOD TRANSFUS SERV,CENT LAB,CH-3012 BERN,SWITZERLAND

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1991年 / 88卷 / 04期

关键词：

D O I：

10.1073/pnas.88.4.1403

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The probable ancestral haplotype for human apolipoprotein B (apoB) has been identified through immunological analysis of chimpanzee and gorilla serum and sequence analysis of their DNA. Moreover, the frequency of this ancestral apoB haplotype among different human populations provides strong support for the African origin of Homo sapiens sapiens and their subsequent migration from Africa to Europe and to the Pacific. The approach used here for the identification of the ancestral human apoB haplotype is likely to be applicable to many other genes.

引用

页码：1403 / 1406

页数：4

共 13 条

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[2]

BUTLER R, 1974, VOX SANG, V26, P485

[3]

BUTLER R, 1990, DNA OTHER POLYMORPHI, P135

[4]

Cavalli-Sforza L. L., 1971, GENETICS HUMAN POPUL, P704