REACTIONS OF THE ALPHA-TOCOPHEROXYL RADICAL IN MICELLAR SOLUTIONS STUDIED BY NANOSECOND LASER FLASH-PHOTOLYSIS

被引：61

作者：

BISBY, RH ^{[1
]}

PARKER, AW ^{[1
]}

机构：

[1] SERC, RUTHERFORD APPLETON LAB, LASER SUPPORT FACIL, DIDCOT OX11 OQX, OXON, ENGLAND

来源：

FEBS LETTERS | 1991年 / 290卷 / 1-2期

关键词：

ALPHA-TOCOPHEROL; VITAMIN-E; RADICAL; ASCORBATE; FLASH PHOTOLYSIS; MICELLE;

D O I：

10.1016/0014-5793(91)81260-F

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Laser flash photolysis of alpha-tocopherol in methanol and in aqueous micellar solutions has been shown to produce the alpha-tocopheroxyl radical. The reaction between the alpha-tocopheroxyl radical and ascorbate in positively charged hexadecyltrimethylammonium chloride (HTAC) micelles occurred with a second order rate constant of 7.2 x 10(7) M-1.S-1, whereas in negatively charged sodium dodecyl sulphate (SDS) micelles the rats constant was only 3.8 x 10(4) M-1.S-1. The alpha-tocopheroxyl radical was found to be relatively long-lived in HTAC micelles (t1/2 is-greater-than-or-equal-to 5 min), allowing the slow disappearance of the alpha-tocopheroxyl radical by reaction with glutathione to be observed.

引用

页码：205 / 208

页数：4

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