APPLICATION OF FAST CYCLIC VOLTAMMETRY TO MEASUREMENT OF ELECTRICALLY EVOKED DOPAMINE OVERFLOW FROM BRAIN-SLICES INVITRO

被引：89

作者：

BULL, DR

PALIJ, P

SHEEHAN, MJ

MILLAR, J

STAMFORD, JA

KRUK, ZL

HUMPHREY, PPA

机构：

[1] UNIV LONDON LONDON HOSP,COLL MED,DEPT PHYSIOL,LONDON E1 2AD,ENGLAND

[2] UNIV LONDON LONDON HOSP,COLL MED,DEPT PHARMACOL,LONDON E1 2AD,ENGLAND

来源：

JOURNAL OF NEUROSCIENCE METHODS | 1990年 / 32卷 / 01期

关键词：

Dopamine; Fast cyclic voltammetry; In vitro; Release; Striatum;

D O I：

10.1016/0165-0270(90)90069-R

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Fast cyclic voltammetry at a carbon fibre microelectrode was used to monitor the time course of dopamine overflow in slices of rat corpus striatum incubated in a brain slice chamber. Dopamine release occurred in response to electrical stimulation. Electrochemical, physiological and pharmacological evidence indicates that release of endogenous dopamine can be measured reliably for up to 9 h and that fast cyclic voltammetry can be used in brain slices for quantitative studies of dopamine release in the CNS. © 1990.

引用

页码：37 / 44

页数：8

共 23 条

[1] QUANTIFICATION OF NORADRENALINE IONTOPHORESIS [J].