IN-VITRO SODIUM-SALICYLATE RELEASE FROM CHITOSAN FILMS

被引：14

作者：

BONVIN, MM

DEBERTORELLO, MM

机构：

[1] Departamento de Farmacia, Facultad de Ciencias Quimicas, Universidad Nacional de Córdoba, Córdoba, 5016

来源：

POLYMER BULLETIN | 1993年 / 31卷 / 03期

关键词：

D O I：

10.1007/BF00692966

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 [高分子化学与物理]; 080501 [材料物理与化学]; 081704 [应用化学];

摘要：

In order to evaluate the applicability of chitosan membranes in controlled release systems, a reservoir-type device was designed. Sodium salicylate was chosen as model drug. The rate of release was measured in water at 37-degrees +/- 0.5-degrees-C and the amount of drug released was determined by spectrophotometric analysis. The results showed that sodium salicylate release followed a zero order kinetics.

引用

页码：375 / 379

页数：5

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